STK40 Polyclonal Antibody

Reddot Biotech

STK40 Polyclonal Antibody

5

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

0.3 mg/ml

Unconjugated

STK40

serine/threonine kinase 40

Ser/Thr-like kinase; serine/threonine-protein kinase 40; SgK495; SHIK; SINK-homologous serine/threonine-protein kinase; sugen kinase 495

Rabbit

IgG

STK40 (Serine/threonine-protein kinase 40), also known as Sugen kinase 495, is a 435 amino acid protein kinase that may be a negative regulator of NFkappaB and p53-mediated gene expression. Localized to both the cytoplasm and the nucleus, STK40 is ubiquitously expressed. STK40 has a central serine/threonine protein kinase domain and is homologous to TRB-3, a protein that regulates activation of MAP kinases and inhibits NFkappaB-mediated gene transcription. Similarly, overexpression of STK40 inhibits NFkappaB activation triggered by TNF and also inhibits p53-mediated transcription. There are four named isoforms of STK40 that are produced as a result of alternative splicing.

Human, Mouse, Rat

-20°C

12352203