AC1 Antibody, Biotin conjugated
CSB-PA324434LD01ADX
Overview
- SupplierCusabio
- Product NameAC1 Antibody, Biotin conjugated
- Delivery Days Customer20
- ApplicationsELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateBiotin
- HostRabbit
- IsotypeIgG
- Scientific DescriptionEssential for the replication of viral ssDNA. The closed circular ssDNA genome is first converted to a superhelical dsDNA. Rep binds a specific region at the genome origin of replication. It introduces an endonucleolytic nick within the conserved sequence 5\-TAATATTAC-3\ in the intergenic region of the genome present in all geminiviruses, thereby initiating the rolling circle replication (RCR). Following cleavage, binds covalently to the 5\-phosphate of DNA as a tyrosyl ester. The cleavage gives rise to a free 3\-OH that serves as a primer for the cellular DNA polymerase. The polymerase synthesizes the (+) strand DNA by rolling circle mechanism. After one round of replication, a Rep-catalyzed nucleotidyl transfer reaction releases a circular single-stranded virus genome, thereby terminating the replication. Displays origin-specific DNA cleavage, nucleotidyl transferase, ATPase and helicase activities (By similarity).
- ReactivityVirus
- Storage Instruction-20°C or -80°C
- UNSPSC12352203