ATG4B Antibody, FITC conjugated

Cusabio

ATG4B Antibody, FITC conjugated

20

Research Use Only

Polyclonal

FITC

Rabbit

IgG

Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.

Human

-20°C or -80°C

12352203