CAV1 Antibody
CSB-PA870052
ApplicationsImmunoFluorescence, Western Blot, ELISA
Product group Antibodies
ReactivityHuman
Overview
- SupplierCusabio
- Product NameCAV1 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- HostRabbit
- IsotypeIgG
- Scientific DescriptionMay act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity By similarity. Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway. Wei Zhang, J. Biol. Chem., Jun 2000; 275: 20717. Rosalia Mora, J. Biol. Chem., Sep 1999; 274: 25708. Isabella Parolini, J. Biol. Chem., Sep 1999; 274: 25718. Phuong U. Le, J. Biol. Chem., Jan 2002; 277: 3371 - 3379.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203