CD146 Antibody

Cusabio

CD146 Antibody

20

Flow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Monoclonal

8A10

Unconjugated

IgG

Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.

Human

-20°C or -80°C

12352203