CPEB1 Antibody, FITC conjugated
CSB-PA861184LC01HU
ReactivityHuman
Product group Antibodies
Overview
- SupplierCusabio
- Product NameCPEB1 Antibody, FITC conjugated
- Delivery Days Customer20
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateFITC
- HostRabbit
- IsotypeIgG
- Scientific DescriptionSequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5\-UUUUUAU-3\) within the mRNA 3\-UTR. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradation (By similarity). Involved in the transport of CPE-containing mRNA to dendrites; those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses (By similarity). Its interaction with APLP1 promotes local CPE-containing mRNA polyadenylation and translation activation (By similarity). Induces the assembly of stress granules in the absence of stress.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203