CYP3A4 Antibody

Cusabio

CYP3A4 Antibody

20

Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

Rabbit

IgG

Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,8-cineole 2-exo-monooxygenase. The enzyme also hydroxylates etoposide. Vuoristo M.M., J. Biol. Chem. 270:22873-22881(1995). Mungall A.J., Nature 425:805-811(2003). Lui V.C., Genomics 32:401-412(1996).

Human, Mouse

-20°C or -80°C

12352203