DHRS2 Antibody

Cusabio

DHRS2 Antibody

20

Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

Rabbit

IgG

Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2-propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21. Gabrielli F., Eur. J. Biochem. 232:473-477(1995). Pellegrini S., Biochim. Biophys. Acta 1574:215-222(2002). Suzuki Y., Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.

Human

-20°C or -80°C

12352203