EXO1 Antibody, Biotin conjugated

Cusabio

EXO1 Antibody, Biotin conjugated

20

ELISA

Research Use Only

Polyclonal

Biotin

Rabbit

IgG

5\->3\ double-stranded DNA exonuclease which may also possess a cryptic 3\->5\ double-stranded DNA exonuclease activity. Functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5\ or 3\ to the mismatch. Also exhibits endonuclease activity against 5\-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5\-end of a downstream Okazaki fragment. Required for somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin genes. Essential for male and female meiosis.

Human

-20°C or -80°C

12352203