GAB2 (Ab-623) Antibody

Cusabio

GAB2 (Ab-623) Antibody

20

Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

Rabbit

IgG

Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis. Nishida K., Blood 93:1809-1816(1999). Nagase T., DNA Res. 5:31-39(1998). Salomon A.R., Proc. Natl. Acad. Sci. U.S.A. 100:443-448(2003).

Human, Mouse

-20°C or -80°C

12352203