GPR143 Antibody, HRP conjugated

Cusabio

GPR143 Antibody, HRP conjugated

20

ELISA

Research Use Only

Polyclonal

HRP

Rabbit

IgG

Receptor for tyrosine, L-DOPA and dopamine. After binding to L-DOPA, stimulates Ca(2+) influx into the cytoplasm, increases secretion of the neurotrophic factor SERPINF1 and relocalizes beta arrestin at the plasma membrane; this ligand-dependent signaling occurs through a G(q)-mediated pathway in melanocytic cells. Its activity is mediated by G proteins which activate the phosphoinositide signaling pathway. Plays also a role as an intracellular G protein-coupled receptor involved in melanosome biogenesis, organization and transport.

Human

-20°C or -80°C

12352203