GZMA Antibody

Cusabio

GZMA Antibody

20

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

Rabbit

IgG

Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after \\\Lys-31\\\ and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after \\\Lys-189\\\, which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA.

Human

-20°C or -80°C

12352203