IGF1R (Ab-1346) Antibody

Cusabio

IGF1R (Ab-1346) Antibody

20

Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

Rabbit

IgG

This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1. Adams, T.E. et al. (2000) Cell. Mol. Life Sci. 57, 1050-1093 Baserga, R. et al. (2000) Oncogene 19, 5574-5581 Scheidegger, K.J. et al. (2000) J. Biol. Chem. 275, 38921-38928. OConnor R, et al. Mol Cell Biol 1997 Jan; 17(1): 427-35

Human, Mouse, Rat

-20°C or -80°C

12352203