KDM1B Antibody, Biotin conjugated
CSB-PA822748LD01HU
ApplicationsELISA
Product group Antibodies
ReactivityHuman
Overview
- SupplierCusabio
- Product NameKDM1B Antibody, Biotin conjugated
- Delivery Days Customer20
- ApplicationsELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateBiotin
- HostRabbit
- IsotypeIgG
- Scientific DescriptionHistone demethylase that demethylates \Lys-4\ of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated \Lys-4\ of histone H3. Has no effect on tri-methylated \Lys-4\, mono-, di- or tri-methylated \Lys-9\, mono-, di- or tri-methylated \Lys-27\, mono-, di- or tri-methylated \Lys-36\ of histone H3, or on mono-, di- or tri-methylated \Lys-20\ of histone H4 (By similarity).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203