LRAT Antibody

Cusabio

LRAT Antibody

20

ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

Rabbit

IgG

Transfers the acyl group from the sn-1 position of phosphatidylcholine to all-trans retinol, producing all-trans retinyl esters. Retinyl esters are storage forms of vitamin A. LRAT plays a critical role in vision. It provides the all-trans retinyl ester substrates for the isomerohydrolase which processes the esters into 11-cis-retinol in the retinal pigment epithelium; due to a membrane-associated alcohol dehydrogenase, 11 cis-retinol is oxidized and converted into 11-cis-retinaldehyde which is the chromophore for rhodopsin and the cone photopigments. Ruiz A., J. Biol. Chem. 274:3834-3841(1999). Mondal M.S., Biochemistry 39:5215-5220(2000). Thompson D.A., Nat. Genet. 28:123-124(2001).

Human, Mouse, Rat

-20°C or -80°C

12352203