NXF1 Antibody

Cusabio

NXF1 Antibody

20

Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

Rabbit

IgG

Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm (TAP/NFX1 pathway). The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 components of the TREX complex. ALYREF/THOC4-bound mRNA is thought to be transferred to the NXF1-NXT1 heterodimer for export. Braun I.C., EMBO J. 18:1953-1965(1999). Kang Y., Genes Dev. 13:1126-1139(1999). Bear J., Mol. Cell. Biol. 19:6306-6317(1999).

Human

-20°C or -80°C

12352203