PAN2 Antibody,Biotin conjugated

Catalog number: CSB-PA681391LD01HU_50ug
Brand: Cusabio
Packing: 50 ug
Other sizes: 100 ug
Price: € 138.00
Expected delivery time: 14 days

Product specifications for - PAN2 Antibody,Biotin conjugated

Product group: Antibodies
Category: Primary Antibodies
Application: ELISA
Application note: ELISA,Not yet tested in other applications.
Host: Rabbit
Clonality: Polyclonal
Conjugation: Biotin
Isotype: IgG
Purity: >95%,Protein G purified
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Form supplied: Liquid
Storage instructions: Shipped at 4-¦C. Upon delivery aliquot and store at -20-¦C or -80-¦C. Avoid repeated freeze.
Scientific information: 
Scientific info: Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA when the poly(A) stretch is bound by poly(A)-binding protein (PABP), which is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.
Swiss prot ID: Q504Q3
Additional information: 
Synonyms: CSB-PA681391LD01HU