Phospho-AURKC (Thr236/202) Antibody

Cusabio

Phospho-AURKC (Thr236/202) Antibody

20

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

Rabbit

IgG

Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Plays also a role in meiosis and more particularly in spermatogenesis. Has redundant cellular functions with AURKB and can rescue an AURKB knockdown. Like AURKB, AURKC phosphorylates histone H3 at Ser-10 and Ser-28. Phosphorylates TACC1, another protein involved in cell division, at Ser-228.

Human, Mouse, Rat

-20°C or -80°C

12352203