Phospho-CAV1 (Tyr14) Antibody
CSB-PA263805
ApplicationsImmunoFluorescence, Western Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse, Rat
Overview
- SupplierCusabio
- Product NamePhospho-CAV1 (Tyr14) Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe scaffolding protein encoded by Caveolin-1 is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (a and beta) are encoded by a single transcript from this gene. Zhang Y, et al. (2005) Mol Cell Proteomics. 4(9): 1240-1250. Labrecque L, et al. (2004) J Biol Chem. 279(50): 52132-52140. Fielding PE, et al. (2004) Biochemistry. 43(9): 2578-2586. Labrecque L, et al. (2003) Mol Biol Cell. 14(1): 334-347. Maggi D, et al. (2002) Biochem Biophys Res Commun. 295(5): 1085-1089.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203