Phospho-DNM1L (Ser637) Antibody

Cusabio

Phospho-DNM1L (Ser637) Antibody

20

Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

Rabbit

IgG

Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally regulated apoptosis during neural tube formation. Shin H.-W., J. Biochem. 122:525-530(1997). Hong Y.-R., Biochem. Biophys. Res. Commun. 249:697-703(1998). Imoto M., J. Cell Sci. 111:1341-1349(1998).

Human, Mouse, Rat

-20°C or -80°C

12352203