Phospho-PRKAA1/PRKAA2 (Ser487) Antibody
CSB-PA261465
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
Overview
- SupplierCusabio
- Product NamePhospho-PRKAA1/PRKAA2 (Ser487) Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- HostRabbit
- IsotypeIgG
- Scientific DescriptionResponsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit. Kim JE, et al. (2005) J Proteome Res. 4(4): 1339-1346. Woods A, et al. (2003) J Biol Chem. 278(31): 28434-28442.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203