PTK2B (Ab-402) Antibody

Cusabio

PTK2B (Ab-402) Antibody

20

ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

Rabbit

IgG

Involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. May represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. Interacts with the SH2 domain of Grb2. May phosphorylate the voltage-gated potassium channel protein Kv1.2. Its activation is highly correlated with the stimulation of c-Jun N-terminal kinase activity. Involved in osmotic stress-dependent SNCA Tyr-125 phosphorylation. Gluck SL, et al. (2004) J Clin Invest; 114(12): 1696-1699 Benzing T, et al. (2001) Proc Natl Acad Sci U S A; 98(17): 9784-9789 Tian D, et al. (2002) Mol Cell Biol; 22(8): 2650-2662 Lu Z, et al. (2001) Mol Cell Biol; 21(12): 4016-4031 Krishnan HH, et al. (2006) J Virol; 80(3): 1167-1180

Human, Mouse, Rat

-20°C or -80°C

12352203