Rabbit anti-human CYP1A2 polyclonal antibody

Gel: 6%SDS-PAGE, Lysate: 40 µg, Lan...

Immunohistochemistry of paraffin-em...

Product specifications for - Rabbit anti-human CYP1A2 polyclonal antibody

Overview:
Product group:	Antibodies
Category:	Primary Antibodies
Application:	ELISA, Western Blot, ImmunoHistoChemistry
Application note:	ELISA: 1:2000-1:5000, WB:1:200-1:1000, IHC: 1:50-1:200
Host:	Rabbit
Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG

Properties:
Purity:	Antigen affinity purification
Datasheet:	Datasheet
	Research Use Only
UNSPSC:	12352203
Form supplied:	Liquid
Storage instructions:	Shipped at 4-¦C. Upon delivery aliquot and store at -20-¦C or -80-¦C. Avoid repeated freeze.

Scientific information:
Scientific info:	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown, however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region.
Swiss prot ID:	P05177

Scientific information:

Scientific info:

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown, however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region.

Swiss prot ID:

P05177

Additional information:
Synonyms:	CSB-PA439630

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Product specifications for - Rabbit anti-human CYP1A2 polyclonal antibody