Rabbit anti-human DHCR7 polyclonal antibody

Catalog number: CSB-PA110763_50ul
Brand: Cusabio
Packing: 50 ul
Other sizes: 100 ul
Price: € 138.00
Expected delivery time: 14 days
Immunohistochemistry of paraffin-em...

Product specifications for - Rabbit anti-human DHCR7 polyclonal antibody

Product group: Antibodies
Category: Primary Antibodies
Application: ELISA, ImmunoHistoChemistry
Application note: ELISA: 1:1000-1:2000, IHC: 1:25-1:100
Host: Rabbit
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Purity: Antigen affinity purification
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Form supplied: Liquid
Storage instructions: Shipped at 4-¦C. Upon delivery aliquot and store at -20-¦C or -80-¦C. Avoid repeated freeze.
Scientific information: 
Scientific info: This gene encodes an enzyme that removes the C(7-8) double bond in the B ring of sterols and catalyzes the conversion of 7-dehydrocholesterol to cholesterol. This gene is ubiquitously expressed and its transmembrane protein localizes to the endoplasmic reticulum membrane and nuclear outer membrane. Mutations in this gene cause Smith-Lemli-Opitz syndrome (SLOS), a syndrome that is metabolically characterized by reduced serum cholesterol levels and elevated serum 7-dehydrocholesterol levels and phenotypically characterized by mental retardation, facial dysmorphism, syndactyly of second and third toes, and holoprosencephaly in severe cases to minimal physical abnormalities and near-normal intelligence in mild cases. Alternative splicing results in multiple transcript variants that encode the same protein.
Swiss prot ID: Q9UBM7
Additional information: 
Synonyms: CSB-PA110763