RAD18 Antibody

Cusabio

RAD18 Antibody

20

Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

Rabbit

IgG

E3 ubiquitin-protein ligase involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA. Associates to the E2 ubiquitin conjugating enzyme UBE2B to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on Lys-164. Has ssDNA binding activity. Tateishi S., Proc. Natl. Acad. Sci. U.S.A. 97:7927-7932(2000). Xin H., Nucleic Acids Res. 28:2847-2854(2000). Muzny D.M., Nature 440:1194-1198(2006).

Human, Rat

-20°C or -80°C

12352203