RRM2B Antibody

Cusabio

RRM2B Antibody

20

Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

Rabbit

IgG

Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage. Tanaka H., Nature 404:42-49(2000). Ugai H., Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.

Human, Mouse, Rat

-20°C or -80°C

12352203