SLC22A17 Antibody, FITC conjugated

Cusabio

SLC22A17 Antibody, FITC conjugated

20

Research Use Only

Polyclonal

FITC

Rabbit

IgG

Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis.

Human

-20°C or -80°C

12352203