SMG7 Antibody

Cusabio

SMG7 Antibody

20

ImmunoFluorescence, Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

Rabbit

IgG

Plays a role in nonsense-mediated mRNA decay. Recruits UPF1 to cytoplasmic mRNA decay bodies. Together with SMG5 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation. Ohnishi T., Mol. Cell 12:1187-1200(2003). Nagase T., DNA Res. 3:321-329(1996). Nakajima D., DNA Res. 9:99-106(2002).

Human

-20°C or -80°C

12352203