TRIB3 Antibody, FITC conjugated
CSB-PA847220LC01HU
Overview
- SupplierCusabio
- Product NameTRIB3 Antibody, FITC conjugated
- Delivery Days Customer20
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateFITC
- HostRabbit
- IsotypeIgG
- Scientific DescriptionDisrupts insulin signaling by binding directly to Akt kinases and blocking their activation. May bind directly to and mask the \\\Thr-308\\\ phosphorylation site in AKT1. Binds to ATF4 and inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity. Interacts with MAPK kinases and regulates activation of MAP kinases. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells. Does not display kinase activity. Inhibits the transcriptional activity of DDIT3/CHOP and is involved in DDIT3/CHOP-dependent cell death during ER stress. Can inhibit APOBEC3A editing of nuclear DNA.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203