Human Amyloidbeta (1-38) (FL)... | 27717-96Well | IBL Japan

Product specifications for - Human Amyloidbeta (1-38) (FL) Assay Kit

Overview:
Product group:	Assays
Category:	ELISA / EIA

Properties:
Assay Sample Type:	CSF, Cell culture supernatant
Assay Detection Range:	9.38 ~ 600 pg/mL
Datasheet:	Datasheet
	Research Use Only
UNSPSC:	41116158
Form supplied:	1kit

Scientific information:
Scientific info:	The first case of Alzheimer's disease (AD) was defined and reported in 1907 by the German scientist, Dr. A. Alzheimer. His studies have shown that this is the main cause of dementia in the elderly. The plaques which appear in the brains of individuals who suffer AD are mostly constituted by the Amyloidbeta protein (Abeta). Abeta is a peptide which consists of 40 or 42 (43) amino acids, and reports show that this is cleaved from beta- and gamma- secretase from the amyloid precursor protein. APP is a trans-membrane protein consisting of 695, 751, or 770 amino acids. Reports have shown many variants of Abeta exist and are clarified into the culture supernatant from the APP cDNA transfected mouse neuroblastoma cell. In 2001, Edward H. Koo et al. found that the secretion of Abeta42 decreased by the effect of NSAIDs, and with this, the secretion of Abeta38 increased. NSAIDs is attracting attention as a gamma- secretase modulation and then Abeta38 and Abeta42 have become important object molecules to be measured as indicators for the effect of NSAIDs. This ELISA kit can measure Human Abeta (1-38) which held N-terminal side completely. IBL has many other kinds of Amyloidbeta-related products for AD research. They are very specific assay systems for each target and they can be used according to the purpose of study. The control set is available for sale on request.

Scientific information:

Scientific info:

The first case of Alzheimer's disease (AD) was defined and reported in 1907 by the German scientist, Dr. A. Alzheimer. His studies have shown that this is the main cause of dementia in the elderly. The plaques which appear in the brains of individuals who suffer AD are mostly constituted by the Amyloidbeta protein (Abeta). Abeta is a peptide which consists of 40 or 42 (43) amino acids, and reports show that this is cleaved from beta- and gamma- secretase from the amyloid precursor protein. APP is a trans-membrane protein consisting of 695, 751, or 770 amino acids. Reports have shown many variants of Abeta exist and are clarified into the culture supernatant from the APP cDNA transfected mouse neuroblastoma cell. In 2001, Edward H. Koo et al. found that the secretion of Abeta42 decreased by the effect of NSAIDs, and with this, the secretion of Abeta38 increased. NSAIDs is attracting attention as a gamma- secretase modulation and then Abeta38 and Abeta42 have become important object molecules to be measured as indicators for the effect of NSAIDs. This ELISA kit can measure Human Abeta (1-38) which held N-terminal side completely. IBL has many other kinds of Amyloidbeta-related products for AD research. They are very specific assay systems for each target and they can be used according to the purpose of study. The control set is available for sale on request.

Additional information:
Synonyms:	27717; IBL Japan; Amyloid Beta Aβ 1-38 Full Length Human ELISA; Alzheimer's Disease / Amyloid beta / Amyloid-beta / Amyloid Beta / Abeta / Beta Amyloid

Find the product you need

News

Human Amyloidbeta (1-38) (FL) Assay Kit

Product specifications for - Human Amyloidbeta (1-38) (FL) Assay Kit

Login

Find the product you need

News

Human Amyloidbeta (1-38) (FL) Assay Kit

Product specifications for - Human Amyloidbeta (1-38) (FL) Assay Kit