Find the product you need

News

Human ANGPTL2 Assay Kit

Catalog number: 27745-96Well
Brand: IBL Japan
Packing: 96well
Price: On Request
Expected delivery time: 10 days
Quantity:
Spin UpSpin Down

Product specifications for - Human ANGPTL2 Assay Kit

Overview: 
Product group: Assays
Category: ELISA / EIA
Species: Human
Conjugation: HRP
Properties: 
Assay Sample Type: Serum, EDTA-plasma, Cell culture supernatant
Assay Detection Range: 0.05 ~ 3.5 ng/mL
Datasheet: Datasheet
  Research Use Only
UNSPSC: 41116158
Form supplied: 1kit
Scientific information: 
Scientific info: Angiopoietin-like proteins (ANGPTLs) are secretory form proteins which are similar in structure to angiopoietin which is an angiogenesis factor, and 7 ANGPTLs have been identified. ANGPTL2 has been found to affect vascular cells and monocytes, and it have also been known that ANGPTL3 and ANGPTL4 play important roles in llipid metabolism and AGF (Angiopoietin-like growth factor)/ANGPTL6 plays in energy metabolism. These various biological effects of ANGPTL family are attracting attention as a new target of strategy against lifestyle-related diseases like metabolic syndrome or cancer. There is a report that high level of ANGPTL2 in blood observed in individuals who suffer adipsity, strong insulin resistance, diabetes and arteriosclerosis. This kit is a quantitative ELISA kit which can measure ANGPTL2 concentration in human serum or plasma.
Additional information: 
Synonyms: 27745; IBL Japan; ANGPTL2 Human ELISA
Charan M, Dravid P, Cam M, et al. Tumor secreted ANGPTL2 facilitates recruitment of neutrophils to the lung to promote lung pre-metastatic niche formation and targeting ANGPTL2 signaling affects metastatic disease. Oncotarget. 2020;11(5):510-522. Read more
Satou G, Maji D, Isamoto T, Oike Y, Endo M. UV-B-activated B16 melanoma cells or HaCaT keratinocytes accelerate signaling pathways associated with melanogenesis via ANGPTL 2 induction, an activity antagonized by Chrysanthemum extract. Exp Dermatol. 2019;28(2):152-160. Read more
Thorin-trescases N, Thorin E. High Circulating Levels of ANGPTL2: Beyond a Clinical Marker of Systemic Inflammation. Oxid Med Cell Longev. 2017;2017:1096385. Read more
Tian Z, Miyata K, Morinaga J, et al. Circulating ANGPTL2 Levels Increase in Humans and Mice Exhibiting Cardiac Dysfunction. Circ J. 2018;82(2):437-447. Read more
Oike Y, Tian Z, Miyata K, Morinaga J, Endo M, Kadomatsu T. ANGPTL2　- A New Causal Player in Accelerating Heart Disease Development in the Aging. Circ J. 2017;81(10):1379-1385. Read more
Tian Z, Miyata K, Kadomatsu T, et al. ANGPTL2 activity in cardiac pathologies accelerates heart failure by perturbing cardiac function and energy metabolism. Nat Commun. 2016;7:13016. Read more
Hata J, Mukai N, Nagata M, et al. Serum Angiopoietin-Like Protein 2 Is a Novel Risk Factor for Cardiovascular Disease in the Community: The Hisayama Study. Arterioscler Thromb Vasc Biol. 2016;36(8):1686-91. Read more
Yoshinaga T, Shigemitsu T, Nishimata H, Takei T, Yoshida M. Angiopoietin-like protein 2 is a potential biomarker for gastric cancer. Mol Med Rep. 2015;11(4):2653-8. Read more
Ide S, Toiyama Y, Shimura T, et al. Angiopoietin-Like Protein 2 Acts as a Novel Biomarker for Diagnosis and Prognosis in Patients with Esophageal Cancer. Ann Surg Oncol. 2015;22(8):2585-92. Read more
Horiguchi H, Endo M, Miyamoto Y, et al. Angiopoietin-like protein 2 renders colorectal cancer cells resistant to chemotherapy by activating spleen tyrosine kinase-phosphoinositide 3-kinase-dependent anti-apoptotic signaling. Cancer Sci. 2014;105(12):1550-9. Read more
See All