Human FGF23 (intact) ELISA

Catalog number: BI-20700
Brand: Biomedica
Packing: 96 tests
Price: On Request
Expected delivery time: 7 days

Product specifications for - Human FGF23 (intact) ELISA

Product group: Assays
Category: ELISA / EIA
Application note: ELISA
Species: Human
Reactivity note: human
Molecular weight: 26 kDa
Assay Sensitivity: 5.4 pg/ml (= 0.21 pmol/l)
Assay Specificity: Fibroblast Growth Factor-23 intact, FGF23 intact
Assay Precision: intra-assay: 8%, inter-assay: 6%
Assay Sample Type: EDTA plasma, heparin plasma, citrate plasma, serum, urine, cell culture supernatant
Assay Time: 3 h / 30 min
Assay Detection Range: 0-1600 pg/ml (= 0 - 60.8 pmol/l)
Datasheet: Datasheet
  Research Use Only
UNSPSC: 41116133
Scientific information: 
Scientific info: Product Characteristics: The Biomedica FGF23 (intact) human ELISA kit is fully validated according to FDA/ICH/EMEA guidelines for the quantitative measurement of intact FGF23 levels in plasma samples (EDTA, heparin and citrate). The FGF23 (intact) human can additionally be used for the measurement of intact FGF23 in serum, urine and cell culture supernatant. Biomedica's FGF23 (intact) human ELISA is CE certified and approved for in-vitro diagnostic use in the EU.Target information:FGF23 (fibroblast growth factor 23) is a 32-kDa protein with 251 amino acids that is proteolytically processed between arginine179 and serine180 to generate N-terminal and C-terminal fragments. FGF23 is mainly secreted by osteocytes and controls phosphate and 1,25(OH)2 vitamin D homeostasis. The intact form of FGF23 is biologically active.
Gene ID: 8074
Swiss prot ID: Q9GZV9
Safety information: 
Additional information: 
Synonyms: BI-20700; Biomedica Gruppe
Crotti C et al., “Tumor induced osteomalacia: A single center experience on 17 patients.” Bone. (2021); 152:116077. Read more
Chu C et al., “C-terminal and intact FGF23 in kidney transplant recipients and their associations with overall graft survival.” BMC Nephrol. (2021) Apr 8;22(1):125. Read more
Koljonen L et al., “ Phosphate Concentrations and Modifying Factors in Healthy Children From 12 to 24 Months of Age.” J Clin Endocrinol Metab. (2021); 27;106(10):2865-2875. Read more
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