Human Glucagon ELISA

Catalog number: 10-1271-01
Brand: Mercodia
Packing: 1x 96 wells
Price: On Request
Expected delivery time: 4 days
Quantity:

Product specifications for - Human Glucagon ELISA

Overview: 
Product group: Assays
Category: ELISA / EIA
Application note: Mercodia Glucagon ELISA is an assay intended to measure the pancreatic hormone glucagon in plasma and serum. Glucagon measurements are used in the diagnosis and treatment of patients with various disorders of carbohydrate metabolism, including diabetes mellitus, hypoglycemia, and hyperglycemia.
Properties: 
Assay Detection Range: 1.5 - 130 pmol/L (5 - 453 pg/mL)
Datasheet: Datasheet
  CE and IVD Certification
UNSPSC: 41116158
Scientific information: 
Scientific info: The Mercodia Glucagon ELISA is a CE/IVD-marked, highly specific and sensitive immunoassay for measuring glucagon in plasma and serum.

The highly specific monoclonal antibodies used in this assay enables accurate determination of glucagon without significant cross-reactivity to other circulating pro-glucagon derived peptides, like for instance glicentin. Circulating glicentin often cause cross-reactivity problems because of its shared sequence with glucagon.

Advantages
- Low sample volume - 25uL
- No purification of samples
- High sensitivity - 1 pmol/L
- Easy-to-use protocol
- Little or no cross-reactivity to peptides oxyntomodulin, glicentin, mini-glucagon, GLP-1, GLP2 and GRPP.
- CE/IVD marked
Safety information: 
MSDS: MSDS
Additional information: 
Synonyms: 10-1271-01; Mercodia Glucagon ELISA
Manell H, Staaf J, Manukyan L, et al. Altered Plasma Levels of Glucagon, GLP-1 and Glicentin During OGTT in Adolescents With Obesity and Type 2 Diabetes. J Clin Endocrinol Metab. 2016;101(3):1181-9. Read more
Hall MJ, Adin CA, Borin-crivellenti S, et al. Pharmacokinetics and pharmacodynamics of the glucagon-like peptide-1 analog liraglutide in healthy cats. Domest Anim Endocrinol. 2015;51:114-21. Read more
Wewer albrechtsen NJ, Hartmann B, Veedfald S, et al. Hyperglucagonaemia analysed by glucagon sandwich ELISA: nonspecific interference or truly elevated levels?. Diabetologia. 2014;57(9):1919-26. Read more
Chow SZ, Speck M, Yoganathan P, et al. Glycoprotein 130 receptor signaling mediates α-cell dysfunction in a rodent model of type 2 diabetes. Diabetes. 2014;63(9):2984-95. Read more
Malmgren S, Ahrén B. DPP-4 inhibition contributes to the prevention of hypoglycaemia through a GIP-glucagon counterregulatory axis in mice. Diabetologia. 2015;58(5):1091-9. Read more