Catalog number: SK-1204
Brand: Biomedica
Packing: 98 tests
Price: On Request
Expected delivery time: 7 days

Product specifications for - Human NT-proBNP ELISA

Product group: Assays
Category: ELISA / EIA
Application note: ELISA
Species: Human
Reactivity note: human
Molecular weight: 8.475 kDa
Assay Sensitivity: 3.0 pmol/l (= 25.4 pg/ml)
Assay Specificity: NT-proBNP, N-Terminal pro-Brain Natriuretic Peptide
Assay Precision: intra-assay: 3%, inter-assay: 7%
Assay Sample Type: Serum, EDTA plasma
Assay Time: 3 h / 30 min
Assay Detection Range: 10-640 pmol/l
Datasheet: Datasheet
  Research Use Only
UNSPSC: 41116133
Scientific information: 
Scientific info: Product Characteristics: The Biomedica human NT-proBNP Sandwich ELISA kit is a test that is intended for the quantitative measurement of N-terminal pro brain natriuretic peptide levels in human serum and EDTA plasma. The Biomedica NT-proBNP ELISA is a highly recognized test with65 NT-proBNP ELISA specific publications to date, CE certified and approved for in-vitro diagnistic use in the EU.Target information: BNP is mainly expressed by ventricular myocardium in response to volume overload and increased filling pressure. BNP has a cleavable signal sequence. Mature BNP consists of 108 amino acids (proBNP or BNP-108), and undergoes cleavage resulting in physiologically active BNP-32 and additional C-terminal fragments, along with a physiologically inactive N-terminal peptide comprising amino acids 1-76, which is further degraded proteolytically. BNP has a key role in cardiovascular homeostasis with biological actions including natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. A high concentration of BNP in the bloodstream is indicative of heart failure.
Gene ID: 4879
Swiss prot ID: P16860
Safety information: 
Additional information: 
Synonyms: SK-1204; Biomedica Gruppe; BNP; BNPT; natriuretic peptide; Natriuretic Peptide B; NT proBNP; NT-proBNP; proBNP
Bellagambi FG et al., “Determination and stability of N-terminal pro-brain natriuretic peptide in saliva samples for monitoring heart failure.” Sci Rep. (2021); 11(1):13088 Read more
Hollstein T et al., “Effect of various weight loss interventions on serum NT-proBNP concentration in severe obese subjects without clinical manifest heart failure.” Sci Rep. (2021); 11(1):10096. Read more
Kelly DM et al., “Associations of blood biomarkers with glomerular filtration rate in patients with TIA and stroke: population-based study.” Stroke Vasc Neurol. (2021); Mar;6(1):48-56. Read more
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