Human Osteoprotegerin ELISA

Catalog number: BI-20403
Brand: Biomedica
Packing: 96 tests
Price: On Request
Expected delivery time: 7 days

Product specifications for - Human Osteoprotegerin ELISA

Product group: Assays
Category: ELISA / EIA
Application note: ELISA
Species: Human
Reactivity note: human
Molecular weight: 60 kDa (monomer)
Assay Sensitivity: 0.07 pmol/l (= 1.4 pg/ml)
Assay Specificity: Osteoprotegerin, OPG
Assay Precision: intra-assay: 3%, inter-assay: 5%
Assay Sample Type: Serum, EDTA plasma, heparin plasma, citrate plasma
Assay Time: 4 h / 1 h / 30 min
Assay Detection Range: 1.25-20 pmol/l
Datasheet: Datasheet
  Research Use Only
UNSPSC: 41116133
Scientific information: 
Scientific info: Product Characteristics: The Biomedica human Osteoprotegerin (OPG/TNFRSF11B) Sandwich ELISA kit is a quick day test intended for the quantitative measurement of OPG levels in serum and plama samples (EDTA, citrate and heparin). The human OPG Sandwich ELISA is highly recognised with over 180 OPG ELISA specific references to date, CE certified and approved for in-vitro diagnostic use in the EU. Target information: Osteoprotegerin (OPG) or osteoclast inhibitory factor (OCIF) is a glycoprotein of the TNF receptor superfamily 11b. OPG is synthesized as a monomer of 380 amino acids and is assembled as a homodimer within the cell, and then secreted mainly as a disulfide-linked homodimer into the extracellular compartment. OPG is produced by many different tissues and cell types including osteoblasts. OPG is a negative regulator of bone resorption by acting as decoy receptor for RANKL, thus neutralizing its function in osteoclastogenesis. This glycoprotein is also involved in the regulation of vascular calcification.
Gene ID: 4982
Swiss prot ID: O00300
Safety information: 
Additional information: 
Synonyms: BI-20403; Biomedica Gruppe; OCIF; Osteoprotegerin; PDB5; TNFRSF11B; TR1
Del Toro R et al., “Association of bone biomarkers with advanced atherosclerotic disease in people with overweight/obesity.” Endocrine. (2021); 73(2):339-346. Read more
Zeng Set al., “Osteoprotegerin is an independent risk factor predicting death in stable renal transplant recipients.” Clin Nephrol. (2021) 96(3):129-137. Read more
Gómez-Vaquero C et al., “Relation of the Serum Levels of DKK-1 and Osteoprotegerin with Bone Mass in Tightly Controlled Rheumatoid Arthritis.” Curr Rheumatol Rev. (2021);17(1):101-108. Read more
All Citations Read more