Human Oxidized LDL ELISA

Catalog number: 10-1143-01
Brand: Mercodia
Packing: 1 x 96 wells
Price: On Request
Expected delivery time: 4 days
Quantity:

Product specifications for - Human Oxidized LDL ELISA

Overview: 
Product group: Assays
Category: ELISA / EIA
Application note: The Mercodia Oxidized LDL ELISA kit is intended to be used for the in vitro quantitative measurement of oxidized low density lipoproteins (oxidized LDL) in human serum or plasma. Lipoprotein measurements are used in the diagnosis and treatment of lipid disorders (such as diabetes mellitus), atherosclerosis, and various liver and renal diseases.
Properties: 
Assay Detection Range: 1.4 - 19.0 mU/L (9 - 125 U/L when multiplied with dilution factor)
Datasheet: Datasheet
  CE and IVD Certification
UNSPSC: 41116158
Scientific information: 
Scientific info: Mercodia oxidized LDL ELISA is a unique sandwich ELISA based on the proprietary mouse monoclonal antibody 4E6, which is directed against a conformational epitope in oxidized ApoB-100. Elevated plasma levels of oxidized LDL are associated with higher cardiovascular risk and higher incidence of metabolic diseases, i.e. metabolic syndrome, obesity and type 2 diabetes. Also sub-clinical atherosclerosis, kidney and liver diseases are associated with increased levels of oxidized LDL.

Advantages
- Oxidized LDL is a specific causal biomarker of the atherosclerotic disease process
- Oxidized LDL is an established biomarker/biosensor of oxidative stress
- Documented in more than 1300 clinical and experimental studies
- Measures minimally oxidized LDL that has reached the level of oxidation required for scavanger-mediated uptake by macrophages
- Gives an accurate measurement of the physiological signalling to the scavenging macrophages that will create foam cells, vascular inflammation and atherosclerosis
- CE/IVD marked
- Controls included in the kit
Safety information: 
MSDS: MSDS
Additional information: 
Synonyms: 10-1143-01; Mercodia Oxidized LDL ELISA
Spoto, B. et al. Oxidized LDL, Gamma-Glutamyltransferase and Adverse Outcomes in Older Adults. J. Am. Geriatr. Soc. 65, e77–e82 (2017). Read more
Kaikkonen JE, Kresanov P, Ahotupa M, et al. High serum n6 fatty acid proportion is associated with lowered LDL oxidation and inflammation: the Cardiovascular Risk in Young Finns Study. Free Radic Res. 2014;48(4):420-6. Read more
Lerman RH, Desai A, Lamb JJ, Chang JL, Darland G, Konda VR. A Phytochemical-rich Multivitamin-multimineral Supplement Is Bioavailable and Reduces Serum Oxidized Low-density Lipoprotein, Myeloperoxidase, and Plasminogen Activator Inhibitor-1 in a Four-week Pilot trial of Healthy Individuals. Glob Adv Health Med. 2014;3(2):34-9. Read more
Verhoeven V, Van der auwera A, Van gaal L, et al. Can red yeast rice and olive extract improve lipid profile and cardiovascular risk in metabolic syndrome?: A double blind, placebo controlled randomized trial. BMC Complement Altern Med. 2015;15:52. Read more