Human total soluble Neuropilin-1 ELISA

Catalog number: BI-20409
Brand: Biomedica
Packing: 96 tests
Price: € 701.00
Expected delivery time: 7 days

Product specifications for - Human total soluble Neuropilin-1 ELISA

Product group: Assays
Category: ELISA / EIA
Application note: ELISA
Reactivity note: human
Molecular weight: 69.7 kDa
Assay Sensitivity: 0.09 nmol/l (= 6.3 ng/ml)
Assay Specificity: total Neuropilin-1, NRP-1
Assay Precision: intra-assay: 11%, inter-assay: 10%
Assay Sample Type: Serum, EDTA plasma, heparin plasma, citrate plasma
Assay Time: 30 min / 2 h / 1 h / 30 minn
Assay Detection Range: 0.37-12 nmol/l
Datasheet: Datasheet
  Research Use Only
UNSPSC: 41116133
Scientific information: 
Scientific info: Product Characteristics: The Biomedica human total soluble Neuropilin-1 (NRP-1) Sandwich ELISA kit is a reliable day test that is intended for the quantitative measurement of Neuropilin-1 levels in humanserum, EDTA plasma, heparin plasma and citrate plasma samples. Target information: Neuropilin-1 is an essential cell surface receptor functioning in many key biological processes including the cardiovascular, neuronal, and immune systems. It is expressed by a variety of cells and tissues, e.g. the transmembrane protein is expressed by neuronal cells, endothelial cells, vascular smooth muscle cells, cardiomyocytes, multiple tumor cell lines and neoplasms, osteoblasts, naïve T cells or platelets. NRP1 is described to stimulate osteoblast differentiation, to act as potential biomarker for the prediction of heart failure outcome or to play a role in renal fibrogenesis. As a co-receptor for VEGF, NRP1 is a potential target for cancer therapies.
Gene ID: 8829
Swiss prot ID: O14786
Safety information: 
Additional information: 
Synonyms: BI-20409; Biomedica Gruppe
Rachner TD et al., "Soluble Neuropilin-1 is an independent marker of poor prognosis in early breast cancer.” J Cancer Res Clin Oncol. (2021) 147(8):2233-2238. Read more
Gadermaier et al., “Characterization of a sandwich ELISA for quantification of total human soluble neuropilin-1.” J Clin Lab Anal. (2019) 33(7):e22944. Read more
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