Human total soluble Neuropilin-1 ... | BI-20409 | Biomedica - Bio-Connect Diagnostics

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Product specifications for - Human total soluble Neuropilin-1 ELISA

Overview:
Product group:	Assays
Category:	ELISA / EIA
Application note:	ELISA
Reactivity note:	human

Properties:
Molecular weight:	69.7 kDa
Assay Sensitivity:	0.09 nmol/l (= 6.3 ng/ml)
Assay Specificity:	total Neuropilin-1, NRP-1
Assay Precision:	intra-assay: 11%, inter-assay: 10%
Assay Sample Type:	Serum, EDTA plasma, heparin plasma, citrate plasma
Assay Time:	30 min / 2 h / 1 h / 30 minn
Assay Detection Range:	0.37-12 nmol/l
Datasheet:	Datasheet
	Research Use Only
UNSPSC:	41116133

Scientific information:
Scientific info:	Product Characteristics: The Biomedica human total soluble Neuropilin-1 (NRP-1) Sandwich ELISA kit is a reliable day test that is intended for the quantitative measurement of Neuropilin-1 levels in humanserum, EDTA plasma, heparin plasma and citrate plasma samples. Target information: Neuropilin-1 is an essential cell surface receptor functioning in many key biological processes including the cardiovascular, neuronal, and immune systems. It is expressed by a variety of cells and tissues, e.g. the transmembrane protein is expressed by neuronal cells, endothelial cells, vascular smooth muscle cells, cardiomyocytes, multiple tumor cell lines and neoplasms, osteoblasts, naïve T cells or platelets. NRP1 is described to stimulate osteoblast differentiation, to act as potential biomarker for the prediction of heart failure outcome or to play a role in renal fibrogenesis. As a co-receptor for VEGF, NRP1 is a potential target for cancer therapies.
Gene ID:	8829
Swiss prot ID:	O14786

Safety information:
MSDS:	MSDS

Additional information:
Synonyms:	BI-20409; Biomedica Gruppe

Rachner TD et al., "Soluble Neuropilin-1 is an independent marker of poor prognosis in early breast cancer.” J Cancer Res Clin Oncol. (2021) 147(8):2233-2238.

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Gadermaier et al., “Characterization of a sandwich ELISA for quantification of total human soluble neuropilin-1.” J Clin Lab Anal. (2019) 33(7):e22944.

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