S100A8/S100A9 heterodimer (human) ELISA kit

Catalog number: A05083
Brand: Bertin Bioreagent
Packing: 96 wells
Price: On Request
Expected delivery time: 7 days

Product specifications for - S100A8/S100A9 heterodimer (human) ELISA kit

Product group: Assays
Category: ELISA / EIA
Datasheet: Datasheet
UNSPSC: 41116104
Storage instructions: +4-¦C
Scientific information: 
Scientific info: S100A8 and S100A9 are Ca2+ binding proteins that belong to the S100 family, called calgranulin. Calgranulins are endogenous molecules released in response to environmental triggers and cellular damage. Also known as Damage-Associated Molecular Pattern Molecules (DAMPs), these proteins play an important role in a diverse range of physiological and pathological processes, such as host defense, wound healing, autoimmunity, oncogenesis and inflammation, among others. This assay is a sanwich based ELISA kit allowing accurate quantification of S100A8/S100A9 heterodimer in human samples.
Safety information: 
Additional information: 
Synonyms: A05083; Bertin Bioreagent; calprotectin; MRP8/MRP14; Calgranulin A; Calgranulin B; innate immunity; inflammation; trauma; infection; heat; stress; DAMP; calgranulin; COVID-19
Crowe LAN, McLean M, Kitson SM, et al. S100A8 & S100A9: Alarmin mediated inflammation in tendinopathy. Sci Rep. 2019;9(1):1463. Read more
Dubois C, Payen D, Simon S, et al. Top-down and bottom-up proteomics of circulating s100a8/s100a9 in plasma of septic shock patients. J Proteome Res. 2020;19(2):914-925. Read more
Dubois C, Marcé D, Faivre V, et al. High plasma level of S100A8/S100A9 and S100A12 at admission indicates a higher risk of death in septic shock patients. Sci Rep. 2019;9(1):15660. Read more
Holzinger D, Foell D, Kessel C. The role of S100 proteins in the pathogenesis and monitoring of autoinflammatory diseases. Mol Cell Pediatr. 2018;5(1):7. Read more