Calbindin Antibody / CALB1
ORB640001
Overview
- SupplierBiorbyt
- Product NameCalbindin Antibody / CALB1
- Delivery Days Customer16
- ApplicationsELISA
- Applications SupplierELISA (order BSA-free format for coating) ELISA
- CertificationResearch Use Only
- Clone IDCALB1/2364
- IsotypeIgG
- Scientific DescriptionThe family of EF-hand type Ca2+-binding proteins includes Calbindin D28K, Calbindin D9K, S-100 (also designated oncomodulin). Calbindin D28K, also known as calbindin, CALB1, D-28K or vitamin D-dependent calcium-binding protein, is a 261-amino acid protein with 6 EF-hand domains, 4 of which are active calcium-binding domains. Expressed in brain, ovary, uterus, testis, pancreas, liver, kidney and intestine, Calbindin D28K acts as a calcium-buffering agent and alters the activity of the plasma membrane ATPase. In neuronal cells, Calbindin D28K modulates calcium channel activity, calcium transients and intrinsic neuronal firing activity. Also, Calbindin D28K has been implicated to play a role in apoptosis and microtubule function.
- UNSPSC12352203