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Caspase 1 Activity Assay Kit

Research Use Only
ARG82810
Arigo Biolaboratories
Product group Assays
Price on request
Packing Size
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    Caspase 1 Activity Assay Kit
  • Delivery Days Customer
    23
  • Applications
    Functional Assay
  • Assay Detection Range
    5 - 500 micromol/L
  • Assay Time
    ~ 1 hour
  • Certification
    Research Use Only
  • Scientific Description
    This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2012]
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    41116133