CAY10774
T36034
Product group Chemicals
Overview
- SupplierTargetMol Chemicals
- Product NameCAY10774
- Delivery Days Customer1001
- Category SupplierChemical
- Chemical NameCAY10774
- Scientific DescriptionCAY10774 is an inhibitor of the protein-protein interaction between programmed cell death 1 (PD-1) and its ligand PD-L1 (IC50= 15 nM in a homologous time-resolved fret (HTRF) assay).1It increases the activation of Jurkat cells expressing PD-1 in co-culture with artificial antigen-presenting cells (aAPCs) expressing PD-L1 (EC50= 6.6 uM in a reporter assay). CAY10774 increases surface expression of PD-1 on primary human CD4+and CD8+T cells co-cultured with aAPCs.
- Shelf life instruction3 years
- SMILES#Reference to error in column [smiles]
- Storage Instruction-20°
- UNSPSC12352200