CRTAM Polyclonal Antibody
RD75133A
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetCRTAM
Overview
- SupplierReddot Biotech
- Product NameCRTAM Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.3 mg/ml
- ConjugateUnconjugated
- Gene ID56253
- Target nameCRTAM
- Target descriptioncytotoxic and regulatory T cell molecule
- Target synonymsCD355; class-I MHC-restricted T-cell-associated molecule; cytotoxic and regulatory T-cell molecule
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A; MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains. Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo.
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203