DAZL Polyclonal Antibody
RD265805A
ApplicationsImmunoFluorescence
Product group Antibodies
ReactivityHuman, Mouse
TargetDAZL
Overview
- SupplierReddot Biotech
- Product NameDAZL Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoFluorescence
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID1618
- Target nameDAZL
- Target descriptiondeleted in azoospermia like
- Target synonymsDAZ homolog; DAZH; DAZL1; DAZLA; DAZ-like autosomal; deleted in azoospermia-like; deleted in azoospermia-like 1; germline specific RNA binding protein; spermatogenesis gene on the Y-like autosomal; SPGYLA; SPGY-like-autosomal; testis secretory sperm-binding protein Li 204a
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene.
- ReactivityHuman, Mouse
- Storage Instruction-20°C
- UNSPSC12352203