FGFR2/3-IN-1
HY-151903S
Molecular Weight450.51
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NameFGFR2/3-IN-1
- Delivery Days Customer10
- CertificationResearch Use Only
- Molecular FormulaC23H22D3N7O3
- Molecular Weight450.51
- Scientific DescriptionFGFR2/3-IN-1 is a potent and selective FGFR2 and FGFR3 (FGFR) inhibitor with IC50s of 1 nM and 0.5 nM, respectively. FGFR2/3-IN-1 displays >40-fold selectivity over FGFR1/FGFR4 and other kinome. FGFR2/3-IN-1 also inhibits FGFR3 V555L and V555M mutants with IC50s of 2.7 nM and 6.1 nM, respectively[1].
- SMILES[2H]C([2H])(NC(C1=CC(C2=C3N=C(C(C4=CN(N=C4)C(C)C)=CN3N=C2)O[C@@H]5COCC5)=CN=C1)=O)[2H]
- Storage InstructionSee Manual
- UNSPSC12352200