Human CD85j / LIR1 ELISA Kit
![Research Use Only](static/images/certificates/ruo.jpg)
ARG82756
Product group Assays
Overview
- SupplierArigo Biolaboratories
- Product NameHuman CD85j / LIR1 ELISA Kit
- Delivery Days Customer23
- ApplicationsELISA
- Assay PrecisionIntra-Assay CV: 5.3%Inter-Assay CV: 6.4%
- Assay Sensitivity156 pg/ml
- Assay Time~ 5 hours
- CertificationResearch Use Only
- Scientific DescriptionThis gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Storage Instruction2°C to 8°C
- UNSPSC41116133