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Human Ghrelin (total) ELISA Kit

Research Use Only
ARG82773
Arigo Biolaboratories
Product group Assays
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    Human Ghrelin (total) ELISA Kit
  • Delivery Days Customer
    23
  • Applications
    ELISA
  • Assay Detection Range
    Linear range: 0.13 - 1.34 ng/ml
  • Assay Precision
    Intra-Assay CV: < 10%Inter-Assay CV: < 15%
  • Assay Sensitivity
    0.13 ng/ml
  • Assay Specificity
    Cross Reactivity (peptide):Human Ghrelin: 100%Rat Ghrelin: 100%Human Ghrelin 1-27 (O-n-Octanoyl-Ser3): 100%Human Ghrelin 1-27 (O-n-Decanoyl-Ser3): 100%Human Ghrelin (Des-Octanoyl-Ser3): 100%Rat Ghrelin (Des-Octanoyl-Ser3): 100%C-Terminal of Ghrelin: 100%H
  • Assay Time
    ~ 4 hours
  • Certification
    Research Use Only
  • Scientific Description
    This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides, ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty, whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities, including hunger, reward perception via the mesolimbic pathway, gastric acid secretion, gastrointestinal motility, and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake, but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin, including regulating adipocyte function and glucose metabolism. Alternative splicing results in multiple transcript variants. In addition, antisense transcripts for this gene have been identified and may potentially regulate ghrelin-obestatin preproprotein expression. [provided by RefSeq, Nov 2014]
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    41116133