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Human IL10 recombinant protein (Active) (His-tagged, C-ter)

Research Use Only
ARG70032
Arigo Biolaboratories
ApplicationsOther Application
Product group Proteins / Signaling Molecules
Protein IDP22301
Price on request
Packing Size
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    Human IL10 recombinant protein (Active) (His-tagged, C-ter)
  • Delivery Days Customer
    23
  • Applications
    Other Application
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Protein IDP22301
  • Protein Name
    Interleukin-10
  • Scientific Description
    The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011]
  • Storage Instruction
    -20°C
  • UNSPSC
    12352202