GTX01286-pro Image
Human RANK protein, human IgG1 Fc tag (active)
GTX01286-PRO100
Overview
- SupplierGeneTex
- Product NameHuman RANK protein, human IgG1 Fc tag (active)
- Delivery Days Customer9
- Category Supplierprotein
- CertificationResearch Use Only
- Protein IDQ9Y6Q6
- Protein NameTumor necrosis factor receptor superfamily member 11A
- Scientific DescriptionThe protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Aug 2012]
- Storage Instruction-20°C
- UNSPSC12352202