GTX01336-pro Image
Human Vitamin D Receptor protein, His tag
GTX01336-PRO050
Overview
- SupplierGeneTex
- Product NameHuman Vitamin D Receptor protein, His tag
- Delivery Days Customer9
- Category Supplierprotein
- CertificationResearch Use Only
- Protein IDP11473
- Protein NameVitamin D3 receptor
- Scientific DescriptionThis gene encodes vitamin D3 receptor, which is a member of the nuclear hormone receptor superfamily of ligand-inducible transcription factors. This receptor also functions as a receptor for the secondary bile acid, lithocholic acid. Downstream targets of vitamin D3 receptor are principally involved in mineral metabolism, though this receptor regulates a variety of other metabolic pathways, such as those involved in immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Jun 2018]
- Storage Instruction-20°C
- UNSPSC12352202