LH1306
T36046
CAS Number2182653-84-3
Product group Chemicals
Molecular Weight684.838
Overview
- SupplierTargetMol Chemicals
- Product NameLH1306
- Delivery Days Customer1001
- CAS Number2182653-84-3
- Category SupplierChemical
- Chemical NameLH1306
- Molecular FormulaC38H48N6O6
- Molecular Weight684.838
- Scientific DescriptionLH1306 is an inhibitor of the interaction between programmed cell death 1 (PD-1) and its ligand PD-L1 that has an IC50 value of 25 nM in a homologous time-resolved fluorescence (HTRF) assay.1 It increases the activation of Jurkat cells expressing PD-1 in co-culture with U2OS or CHO cells expressing PD-L1 (EC50s = 334 and 4,214 nM, respectively, in reporter assays).
- Shelf life instruction3 years
- SMILESCOc1nc(OCc2cccc(c2C)-c2cccc(COc3ccc(CNCCNC(C)=O)c(OC)n3)c2C)ccc1CNCCNC(C)=O
- Storage Instruction-20°
- UNSPSC12352200